TRT for Men
Diagnosing and treating clinically low testosterone.
Low testosterone treatment starts with symptoms plus morning labs, then a clinician decides whether replacement, a different diagnosis, or watchful waiting fits. Fatigue alone is not a level. A level alone is not a plan.
Low libido, fewer morning erections, a flat mood, loss of strength, and fatigue that is not fixed by a week of sleep. Some men mostly notice irritability. Some notice nothing until a lab done for another reason comes back low. Both can be real. The visit has to hear which one you are.
Sleep apnea, opioid pain medicine, obesity, and a prolactin problem can all push testosterone down. Treating the number and ignoring the cause is how men stay tired on a full dose. If you snore and gasp, say so. A CPAP may matter more than a vial.
Testosterone is higher in the morning. A late-day draw runs low and starts a false story. Fasting is sometimes requested. Follow the slip, not a guess. If you are already on testosterone from another clinic, the lab means something different. Do not stop it the day before unless you were told to.
Estradiol, hematocrit, PSA when age and history call for it, and sometimes LH and FSH to see whether the signal is from the brain or the testes. You do not need to memorize that list. You need to complete what was ordered.
Injections and cream are the common paths. Injections are less daily fuss and more peaks. Cream is daily and can transfer to a partner or a child if you are careless. The cluster pages on each form go further. The choice is adherence plus labs, not a brand preference.
Recheck on the schedule you are given. Men feel good and skip the blood draw, then show up a year later with a hematocrit nobody wanted. The draw is not optional paperwork.
A low level is a finding, not a diagnosis, and the useful visit asks why it is low before it reaches for a prescription. Sleep apnea, obesity, opioid pain medicine, heavy alcohol, and a high prolactin all drag testosterone down, and each has its own fix. Treating the number while one of those runs unchecked is how men stay flat on a full dose and never understand why.
That is also why the labs sometimes include LH and FSH: they help tell whether the signal is failing at the brain or the testes, which changes what the right treatment even is. None of this is you memorizing endocrinology; it is the reason the workup is more than one afternoon tube of blood and a coupon.
Treatment is provided through Jonathan Larson MDPC. Prescriptions require a clinical evaluation; medication is dispensed only when deemed medically necessary. Information here is educational and not a substitute for medical advice.
Related topics in TRT for Men, or head back to the TRT for Men overview.
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